Research

Cryo-EM of Molecular Machines and RNA, Stanford University (1/1/2018)

Use cryo-EM to determine atomic structures of RNA, channels, pumps, transporters, chaperonins, protein degradation machines, and viruses in different functional states in conjunction with biochemical and physiological characterizations.

Collaborators

  • Rhiju Das, Associate Professor of Biochemistry, Stanford University

  • Judith Frydman, Donald Kennedy Chair in the School of Humanities and Sciences and Professor of Genetics, Stanford University

  • Merritt Maduke, Associate Professor of Molecular and Cellular Physiology, Stanford University

  • Ann Arvin, Lucile Salter Packard Professor of Pediatrics and Professor of Microbiology and Immunology, Stanford University

  • Chaitan Khosla, Prof, Stanford University

Unified Data Resource for 3DEM, Stanford University (1/1/2018)

Unified Data Resource for 3DEM

Collaborators

  • Helen Berman, Professor, Rutgers University

From structure to therapy for Huntington’s disease, Stanford University (1/1/2018)

Pathogen-Host interactions studied by cryo-EM and cryo-ET, Stanford University (1/1/2018 - Present)

Our interests span across DNA and RNA viruses infecting from bacteria, archaea and mammals.

CryoET of cells, Stanford University (3/1/2020)

We are developing experimental and computational tools to visualize molecular components in situ

Collaborators

  • William Moerner, Harry S. Mosher Professor and Professor, by courtesy, of Applied Physics, Stanford University

  • John Pauly, Reid Weaver Dennis Professor, Stanford University

  • Serena Yeung, Assistant Professor of Biomedical Data Science and, by courtesy, of Computer Science and of Electrical Engineering, Stanford University

Atomic resolution single particle cryoEM, Stanford University